European Pharmaceutical Manufacturing: Improved fill-and-finish processes reduce the total cost of ownership

Pharmaceutical companies are continuously assessing the productiveness of their filling lines to achieve higher yields with less resources, thereby ensuring high quality standards and maintaining flexibility in the fill-and-finish process. Lower cost, better quality and higher flexibility might appear to be contradictory goals. This article focuses on possible fill-and-finish solutions based on an increased usage of pre-washed and pre-sterilised drug containers compared with traditional filling concepts that work with purchasing non-sterile, so-called ‘bulk’ containers from primary packaging suppliers.