Female laboratory technician in protective clothing looking at a glass vial

EVERIC® freeze Pharmaceutical glass vials for storing drugs at deep-cold temperatures

Name: EVERIC® freeze
Brand: SCHOTT Pharma

Overview

Engineered strength for ultra-low temperature drug storage

Deep-cold storage of drug formulations at temperatures as low as -80°C poses a significant risk of vial breakage. Traditional glass vials often fail under these extreme conditions due to increased internal pressure, flaws introduced during the fill-and-finish process, and the mechanical stresses of freezing and handling. Breakage not only leads to product loss but also threatens the safety and reliability of sensitive pharmaceuticals, such as mRNA and viral vector vaccines.

EVERIC® freeze is an advanced glass vial solution engineered to meet the demanding requirements of deep-cold storage and lyophilization in the pharmaceutical industry. The vial is designed for frozen drug formulations, where product integrity and safety are of the highest importance.

Benefits

Advanced geometry and material for unmatched cold storage performance

Made from FIOLAX® OS glass, EVERIC® freeze features optimized geometry, increased wall thickness, and a homogeneous bottom design. These enhancements ensure superior strength, a reduced risk of breakage, and high cosmetic quality at temperatures as low as -80°C.

Proven CCI at -80 °C

Secure container closure integrity (CCI) even at deep-cold temperatures, maintaining drug integrity in extreme storage conditions

Optimized strength

Increased wall thickness and homogeneous bottom design significantly improve burst pressure performance and reduce the risk of breakage

Enhanced quality

Improved process and inspection enable tighter dimension and cosmetic Acceptable Quality Levels (AQLs)

Superior material and manufacturing

The use of FIOLAX® OS Borosilicate Glass tubing and advanced hot forming processes without glass-to-glass contact results in consistent vial quality

Applications

Purpose-built for mRNA vaccines, viral vectors, and lyophilized drugs

EVERIC® freeze is ideal for pharmaceuticals that require storage at ultra-low temperatures down to -80°C, including mRNA vaccines, viral vector vaccines, and other sensitive biologics. Designed to maintain a stable cold chain temperature for vaccines, it ensures that these temperature-dependent formulations retain their full efficacy.

The glass vial is specifically designed to withstand the stresses of lyophilization (freeze-drying), ensuring both product stability and container integrity throughout the entire cycle. Thanks to its robust design and high dimensional accuracy, EVERIC® freeze is perfectly suited to high-speed, automated production lines and bulk handling scenarios.

EVERIC® freeze glass pharmaceutical vial with chemical composition of glass wall

Specifications


Product Name	Product Name EVERIC® freeze	Product Name EVERIC® plus	Product Name EVERIC® pure	Product Name EVERIC® care	Product Name EVERIC® strong & smooth	Product Name EVERIC® smart	Product Name EVERIC® lyo	Product Name EVERIC® lyo & amber	Product Name EVERIC® amber	Product Name adaptiQ®	Product Name Core Vials
Applications	Applications Drugs that need deep-cold storage down to -80°	Applications Leachable-sensitive drugs in neutral and acidic pH range	Applications Default solution for biologics, diluents, low-filled and high-value drugs	Applications Drugs in high alkaline pH range	Applications Improved bulk fill-and-finish	Applications Track and trace solution	Applications Drugs that need lyophilization	Applications Light sensitive, lyophilized drugs, esp. biologics as ADCs	Applications Light-sensitive drugs, esp. biologics as ADCs	Applications Pre-washed and pre-sterilized for leaner fill-and-finish	Applications Default solution for generics, chemicals
Tubing Container Material	Tubing Container Material FIOLAX® OS (optimized strength)	Tubing Container Material FIOLAX®	Tubing Container Material FIOLAX® CHR (controlled hydrolytic resistance)	Tubing Container Material FIOLAX® CHR (controlled hydrolytic resistance)	Tubing Container Material FIOLAX® OS (optimized strength)	Tubing Container Material FIOLAX®	Tubing Container Material FIOLAX®	Tubing Container Material FIOLAX® amber	Tubing Container Material FIOLAX® amber	Tubing Container Material Depending on bulk vial used	Tubing Container Material FIOLAX®
Format	Format 2-30R	Format 2-50R	Format 2-50R	Format 2R, 6R, 10R	Format 2-30R	Format 2-30R	Format 2-50R	Format 6R, 10R, 20 ml	Format 2R - 10R, 20 ml	Format 2-50R	Format 2-100R
Quality Level	Quality Level TopLine	Quality Level TopLine	Quality Level TopLine	Quality Level TopLine	Quality Level TopLine	Quality Level TopLine	Quality Level TopLine	Quality Level StandardLine	Quality Level StandardLine	Quality Level TopLine	Quality Level StandardLine, TopLine, TopLine Packages
Closure Systems	Closure Systems Stopper + seal	Closure Systems Stopper + seal	Closure Systems Stopper + seal	Closure Systems Stopper + seal	Closure Systems Stopper + seal	Closure Systems Stopper + seal	Closure Systems Stopper + seal	Closure Systems Stopper + seal	Closure Systems Stopper + seal	Closure Systems Stopper + seal or press-fit cap	Closure Systems Stopper + seal
Pre-washed Pre-sterilized	Pre-washed Pre-sterilized Non-sterile available	Pre-washed Pre-sterilized Non-sterile and sterile (adaptiQ®) available	Pre-washed Pre-sterilized Non-sterile and sterile (adaptiQ®) available	Pre-washed Pre-sterilized Non-sterile and sterile (adaptiQ®) available	Pre-washed Pre-sterilized Non-sterile available	Pre-washed Pre-sterilized Non-sterile and sterile (adaptiQ®) available	Pre-washed Pre-sterilized Non-sterile and sterile (adaptiQ®) available	Pre-washed Pre-sterilized Non-sterile and sterile* (adaptiQ®) available	Pre-washed Pre-sterilized Non-sterile and sterile* (adaptiQ®) available	Pre-washed Pre-sterilized Sterile packaging	Pre-washed Pre-sterilized Non-sterile and sterile (only TopLine in adaptiQ®) available
Packaging	Packaging Bulk tray DATASHEET	Packaging Bulk tray, adaptiQ® solution (tray, cup nest) DATASHEET	Packaging Bulk tray, adaptiQ® solution (tray, cup nest) DATASHEET	Packaging Bulk tray, adaptiQ® solution (tray, cup nest) DATASHEET	Packaging Bulk tray DATASHEET	Packaging Bulk tray, adaptiQ® solution (tray, cup nest) DATASHEET	Packaging Bulk tray, adaptiQ® solution (tray, cup nest) DATASHEET	Packaging Bulk tray, adaptiQ® solution (tray, cup nest)	Packaging Bulk tray, adaptiQ® solution (tray, cup nest)	Packaging Pre-sterilized vials tray or cup nest CUP TRAY	Packaging Bulk tray, adaptiQ® solution (tray, cup nest) STANDARDLINE TOPLINE

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*available from Q2 2026

How to choose the ideal packaging for your deep-cold stored drug?

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Diana Löber

Global Product Manager Specialty Vials & adaptiQ®

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