Woman getting an injection from a doctor via syringe.

syriQ BioPure® silicone-free Ready-to-use prefillable silicone-free syringes for biologics

Name: syriQ BioPure® silicone-free
Brand: SCHOTT Pharma

Overview

Safe storage and delivery for silicone-sensitive biologics with prefillable silicone-free syringes

Traditionally, silicone has been used to coat the inner barrel of syringes to reduce injection force. However, silicone can interact with certain biologic drugs, potentially compromising their stability and efficacy.

syriQ BioPure® silicone-free syringes from SCHOTT Pharma offer a breakthrough solution for storing and administering silicone-sensitive biologics. Featuring a glass barrel and plunger completely free of silicone, these prefillable silicone-free syringes help reduce particle load and minimize drug-container interaction, supporting long-term drug stability and patient safety.

Benefits

Superior functionality and drug stability

While the absence of silicone is a major advantage, syriQ BioPure® silicone-free glass syringes go further by delivering lower particulate levels, precise device integration through tight dimensional specifications, and reduced tolerances. The use of FIOLAX® Type I CHR Borosilicate Glass also offers controlled hydrolytic resistance (CHR) and a low extractables and leachables profile.

Superior material

A reliable solution for storing silicone-sensitive biologic drugs in prefillable syringes

Increased safety

Very low particle load and reduced risk of drug-container interaction

Reliable performance

Maintains long-term functionality without silicone

Strong compatibility

Proven compatibility with safety devices and leading autoinjectors

Applications

Advanced syringes for sensitive biologics and home care

syriQ BioPure® silicone-free glass syringes for delivering drug and biological products offer a new generation of sensitive biologics the benefits of prefillable syringes, combining safe storage with reduced drug-container interaction. Thanks to their tight dimensional specifications, syriQ BioPure® silicone-free glass syringes are compatible with a wide range of autoinjectors, making them ideal for home care.

Specifications


Product Name	Product Name syriQ BioPure® silicone-free	Product Name syriQ BioPure®	Product Name syriQ®
Applications	Applications Silicone-sensitive biologics	Applications Biologics, Large-volume drugs	Applications Variety of vaccines, including inactivated (flu shot), live-attenuated (MMR), subunit and recombinant vaccines (HPV) and breakthrough mRNA vaccines, diluent applications
Tubing Container Material	Tubing Container Material FIOLAX® Type I CHR** Borosilicate Glass	Tubing Container Material FIOLAX® Type I (CHR**) Borosilicate Glass	Tubing Container Material FIOLAX® Type I Borosilicate Glass
Format	Format 1 ml staked needle, 2.25 ml staked needle upon request	Format 1 ml lg staked needle, 2.25 ml staked needle, 5.5 ml staked needle	Format 0.5 - 3 ml
Closure Systems	Closure Systems Rigid Needle Shield (RNS)	Closure Systems Rigid Needle Shield (RNS)	Closure Systems syriQ® Rigid Cap (SRC) or OVS®*
Pre-washed, Pre-sterilized	Pre-washed, Pre-sterilized RTU	Pre-washed, Pre-sterilized RTU	Pre-washed, Pre-sterilized RTU
Packaging	Packaging Pre-sterilized syringes in tub- and nest-configuration	Packaging Pre-sterilized syringes in tub- and nest-configuration	Packaging Pre-sterilized syringes in tub- and nest-configuration

		Read More	Read More

Finding the right packaging for biologic drugs

The rapidly growing biologics market is influencing the development of new pharmaceutical primary packaging. New considerations must be taken into account to ensure the stability of the drug throughout its shelf life. In addition, patient care continues to shift from the clinic to a home environment. Read more about how syriQ BioPure® was designed and developed to meet these new requirements.

Cover of a SCHOTT whitepaper on how to find the right packaging for biologic drugs

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