Woman getting an injection from a doctor via syringe.

syriQ BioPure® Silicone-free Syringe Ready-to-use prefillable and silicone-free glass syringes for biologics

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The most stable storage for the most sensitive drugs

Coating the inner barrel surface of a syringe with silicone has long been a necessary method to reduce the injection force required to administer drugs. However, silicone can interact with some drugs and even harm them. In contrast with other technologies designed to mitigate the risks associated with silicone-based coatings, syriQ BioPure® silicone-free syringe feature a glass barrel and plunger free of silicone.

Enhanced by the absence of silicone, the proven quality level of syriQ BioPure® silicone-free opens up new possibilities for the storage and administration of silicone-sensitive drugs in prefillable syringes, saving time for clinicians and improving safety for patients.


SCHOTT syriQ BioPure® silicone-free glass syring

The ideal syringe for complex biologics

By completely eliminating the need for silicone when administering complex biologic drugs, syriQ BioPure ® silicone-free is suitable for highly silicone-sensitive drugs and ophthalmic applications.

Tight dimensional specifications support strong compatibility with a wide range of autoinjectors, making syriQ BioPure® silicone-free syringes ideal for home care.


Learn more about the right packaging for biologic drugs

Read more about how syriQ BioPure® silicone-free glass syringes for delivering drug and biological products were designed and developed to ensure the stability of the drug throughout its shelf life while maintaining a consistent gliding force – even without silicone.

Cover of a SCHOTT whitepaper on how to find the right packaging for biologic drugs

The world’s first silicone-free prefillable glass syringe

To avoid potential contamination with silicone, pharma companies have traditionally chosen vials instead of prefilled syringes. However, with the launch of syriQ BioPure® silicone-free, a new class of drugs can now be stored and administered in prefillable syringes.

While the absence of silicone presents a significant advantage in itself, syriQ BioPure® silicone-free also offers:

  • Lower particulates.

  • Perfect device integration through new dimensional specifications and reduced tolerances.

  • Controlled hydrolytic resistance and a low E&L profile thanks to FIOLAX® CHR Type I Borosilicate Glass.

icon syriq biopure silicone free

New way of storing silicone-sensitive biologic drugs in prefillable syringes

icon low particle

Very low particle load and reduced risk of drug-container interaction

icon reliable functionality

Maintains long-term functionality without silicone

icon compatibility

Proven compatibility with safety devices and autoinjectors


Container material, formats, and packaging

  • Made of high quality FIOLAX® CHR Type I Borosilicate Glass.

  • Format options include 1 ml lg staked needle and 2.25 ml staked needle upon request.

  • Packaged in a nest 100 (1ml lg + 2.25ml) and in a nest 160 (1ml lg).

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Sterile format

Silicone-free syringes: available pre-sterilized in a ready-to-use format

syriQ BioPure® silicone-free syringes from SCHOTT Pharma are manufactured using a state-of-the-art, fully automated production process. The camera-controlled inspection delivers products with consistently high levels of functionality and low cosmetic defects for an efficient fill-and-finish process.

SCHOTT syriQ BioPure® silicone-free syringes in nest and tub packaging
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Dr. Sven Pohle

Dr. Sven Pohle

Global Product Manager Glass Syringes

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