Laboratory technician looking at vials

EVERIC® pure Pharmaceutical glass vials with a homogenous inner surface for unmatched drug stability


Increased drug stability and delamination control

Conventional vials often encounter increased leachable levels, as well as a greater risk of pH shift and delamination. This is caused by a change in the inner surface of the near-bottom region of the vial due to the standard converting process.

The answer to these challenges is EVERIC® pure. Manufactured using glass tubing with a tightened specification for hydrolytic resistance and patented manufacturing technology, these unique glass vials undergo a dedicated release test that monitors leachable levels throughout production. This ensures a homogenous inner surface of the drug container while keeping delamination under control.

Transparent glass vial with close up of surface structure

The ideal container for drug development

Made of pure Type I borosilicate glass (excluding post-treatments), EVERIC® pure vials are ideal for the development of high-value drugs, such as biologics. An optimized inner surface ensures that formulations will be more stable, enabling a broader choice and reducing the risk of time-consuming reformulations.

Thanks to their low leachable levels and ability to reduce pH shift, EVERIC® pure vials offer high stability for terminally sterilized formulations – for example, diluents such as water for injection (WFI) or sodium chloride (NaCl). According to USP <1660>, terminal sterilization is one of the key risk factors for delamination, along with certain buffers. EVERIC® pure vials are the ideal container to keep applications in phosphate buffers or diluents stable.


The safe option right from the start

With EVERIC® pure, SCHOTT Pharma offers a vial with the highest quality level: from tubing over manufacturing to process control. Offering reduced leachable levels, delamination under full control and no need for re-registration, this safe platform is especially crucial during drug development. It enables a wider range of formulation options and a lower risk for re-formulation.

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The safe option from the start

EVERIC® pure is the gold standard for Type I borosilicate glass vials, offering:

  • Delamination under full control
  • Low leachables level, which is especially relevant for low-fill volumes
  • Reduced pH shift and conductivity
  • No re-registration thanks to unchanged glass composition.
Icon leachables

Reduced leachable level

Icon delamination

Controlled delamination ensures drug integrity is not compromised

Icon ph shift

Lower pH shift results in stabilization of the most sensitive drug formulations

Icon documentation regulatory

Unchanged glass composition means no re-registration is required


EVERIC® pure vials – consistent high quality, from materials and manufacturing to process control

  • FIOLAX® CHR glass tubing with a tightened leachable specification is used for all EVERIC® pure vials.

  • We offer a wide format range (2-50R) to provide the ideal solution for all types of drug.

  • EVERIC® pure vials are available in bulk tray packaging or adaptiQ® ready-to-use standardized packaging.

  • EVERIC® pure vials have a TopLine quality level for accurate dimensions and minimal cosmetic defects, as well as a dedicated statistical in-production release test (“Quicktest”), designed to control leachable levels in the heel zone.

Sterile format

Ready-to-use EVERIC® pure

Using the highly standardized secondary packaging adaptiQ®, EVERIC® pure vials are available in a pre-washed and pre-sterilized ready-to-use (RTU) configuration.

Small batches of personalized medications and high-value pharmaceuticals often present challenges for fill-and-finish operations. Not only do they require higher quality containers, but they also require more flexibility, with frequent switching between different medications to avoid costly waste.

adaptiQ® can be processed on a variety of new and existing fill-and-finish lines, keeping vials nested throughout the process, including freeze-drying.

adaptiq Cup 2R over tub
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Get in touch

Diana Löber

Diana Löber

Product Manager Bulk & Sterile Solutions

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